SCHEMBL5191682

SCHEMBL5191682

CNC(=O)Oc1cccc(C)c1C

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
GAA P10253 2/20 0.57
PGR P06401 1/20 0.57
PTGS1 P23219 1/20 0.57
MAPK1 P28482 1/20 0.57
HSD17B10 Q99714 1/20 0.57
ACHE P22303 2/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 3/20 0.48
LMNA P02545 2/20 0.47
HTR1B P28222 1/20 0.46
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30989358 1.00 ALDH1A1 (0.57) ALDH1A1GAAPGRPTGS1MAPK1
SCHEMBL8927729 0.85 ALDH1A1 (0.61) ALDH1A1GAAPGRPTGS1MAPK1
SCHEMBL6883692 0.84 POLB (0.51) ALDH1A1GAAPGRPTGS1MAPK1
SCHEMBL7168856 0.83 ALDH1A1 (0.46) ALDH1A1GAAPGRPTGS1MAPK1
SCHEMBL28891879 0.81 MAPT (0.55) ALDH1A1GAAACHEPOLBMAPT
SCHEMBL1951463 0.81 NLRP3 (0.56) ALDH1A1GAAHSD17B10POLBMAPT
SCHEMBL29525400 0.80 POLB (0.59) ALDH1A1GAAMAPK1ACHEPOLB
SCHEMBL1803105 0.80 POLB (0.59) ALDH1A1GAAMAPK1ACHEPOLB
SCHEMBL6537087 0.80 POLB (0.59) ALDH1A1GAAMAPK1ACHEPOLB
SCHEMBL11210497 0.80 ALDH1A1 (0.55) ALDH1A1GAAPGRPTGS1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO claimed
US-20260068886-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2026-03-12 US disclosed
US-20260033494-A1 PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF TEXAS A & M UNIV SYS (US) 2026-02-05 US disclosed
US-12458025-B2 Plant antimicrobial compositions and methods of use thereof THE TEXAS A & M UNIVERSITY SYSTEM (US) 2025-11-04 US disclosed
US-12364264-B2 Inhibitors of enzymes that confer pesticide resistance APRESLABS LTD. (GB) 2025-07-22 US disclosed
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
US-12121028-B2 Plant antimicrobial compositions and methods of use thereof THE TEXAS A&M UNIVERSITY SYSTEM (US) 2024-10-22 US disclosed
US-20240225003-A1 PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF THE TEXAS A&M UNIVERSITY SYSTEM 2024-07-11 US disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed
US-3966921-A NEMATOCIDES CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed
US-3956306-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3948940-A Pesticidal phthalimido phosphorous ester compounds CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3941829-A PESTICIDE CIBA-GEIGY CORPORATION (US) 1976-03-02 US disclosed
US-3940412-A 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them CIBA-GEIGY AG (CH) 1976-02-24 US disclosed
US-3935224-A 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3933945-A O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458025-B2 Plant antimicrobial compositions and methods of use thereof DDT, CDA, UROD ALDH1A1 3904/4885GAA 719/4885PGR 4504/4885
US-12121028-B2 Plant antimicrobial compositions and methods of use thereof DDT, CDA, UROD ALDH1A1 3904/4885GAA 719/4885PGR 4504/4885
US-20260033494-A1 PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF MYB, DDT, PDE1C ALDH1A1 4194/4885GAA 1245/4885PGR 3935/4885
US-20240225003-A1 PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF DDT, CDA, UROD ALDH1A1 3904/4885GAA 719/4885PGR 4504/4885
US-20260068886-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL CRBN, STUB1, CUL1 ALDH1A1 3713/4885GAA 3440/4885PGR 4485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.