SCHEMBL8927960

SCHEMBL8927960

Nc1c(Br)cc2c(c1Br)Cc1ccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PNMT P11086 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
ACHE P22303 6/20 0.40
BCHE P06276 1/20 0.40
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
EGFR P00533 1/20 0.36
HTR7 P34969 2/20 0.35
HTR2B P41595 2/20 0.35
DRD2 P14416 1/20 0.35
ADRA1D P25100 1/20 0.35
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060999 0.84 PNMT (0.41) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL28156824 0.81 NPC1 (0.46) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL27759342 0.80 PNMT (0.46) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL29453593 0.74 PNMT (0.46) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL784717 0.74 PNMT (0.46) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL3223569 0.74 PNMT (0.39) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL24730420 0.73 PNMT (0.41) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL27692248 0.73 NPC1 (0.48) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL20502811 0.72 PGR (0.38) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL782680 0.71 RAB9A (0.56) KDM4ENPC1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed