SCHEMBL3223569

SCHEMBL3223569

Cc1c(Br)cc2c(c1C)Cc1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.39
ALDH1A1 P00352 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PGR P06401 2/20 0.36
TSHR P16473 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAOA P21397 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14119377 0.85 PNMT (0.36) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL25337616 0.81 PNMT (0.41) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL1871451 0.81 PNMT (0.38) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL14119391 0.79 PGR (0.35) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL31473008 0.79 NPC1 (0.46) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL31473007 0.79 NPC1 (0.46) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL28215357 0.79 PNMT (0.42) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL6060999 0.78 PNMT (0.41) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL20502811 0.77 PGR (0.38) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL14119373 0.76 PGR (0.38) PNMTALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115477587-A Organic compound, application thereof and organic electroluminescent device comprising organic compound 北京鼎材科技有限公司 2022-12-16 CN disclosed
CN-115304601-A Acridine-containing fused ring derivative and application thereof 北京鼎材科技有限公司 2022-11-08 CN disclosed
CN-102276587-B Heterocyclic compound, organic light emitting apparatus and flat display devices SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-14 CN disclosed
US-9478755-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2016-10-25 US disclosed
US-20150221874-A1 ORGANIC OPTOELECTRONIC ELEMENT AND DISPLAY DEVICE COMPRISING SAME CHEIL INDUSTRIES, INC. (KR) 2015-08-06 US disclosed
EP-2889356-A2 ORGANIC PHOTOELECTRIC ELEMENT AND DISPLAY DEVICE COMPRISING SAME Cheil Industries Inc. (KR) 2015-07-01 EP disclosed
US-9067885-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-30 US disclosed
US-9040171-B2 2015-05-26 US disclosed
EP-2392563-B1 Nitrogen containing polycyclic derivatives useful in organic light-emitting devices SAMSUNG DISPLAY CO LTD (KR) 2014-09-17 EP disclosed
CN-101656301-B Organic light emitting diode employing luminescent efficiency improvement layer SAMSUNG DISPLAY CO LTD 2014-09-17 CN disclosed
US-8828561-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2014-09-09 US disclosed
US-20140231779-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME KIM HYUNG-SUN (KR) 2014-08-21 US disclosed
US-8420230-B2 Organic light emitting diode employing luminescent efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-04-16 US disclosed
US-20120305900-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2012-12-06 US disclosed
CN-102276587-A Heterocyclic compound, organic light-emitting device and flat-panel display device 2011-12-14 CN disclosed
US-20110297919-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-12-08 US disclosed
EP-2392563-A1 Nitrogen containing polycyclic derivatives useful in organic light-emitting devices Samsung Mobile Display Co., Ltd. (KR) 2011-12-07 EP disclosed
CN-101656301-A Organic light emitting diode employing luminescent efficiency improvement layer SAMSUNG MOBILE DISPLAY CO LTD 2010-02-24 CN disclosed
US-20100039026-A1 Organic light emitting diode employing luminescent efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120305900-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CRY1 PNMT 897/4885ALDH1A1 191/4885NPC1 2314/4885
US-20110297919-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, CYP2B6 PNMT 3017/4885ALDH1A1 131/4885NPC1 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.