Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHAT | P28329 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodoacetamide SCHEMBL3286706 | 0.84 | SNCA (0.42) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL29483445 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL483213 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL8928013 | 0.81 | MAPT (0.40) | KMT2AMEN1MAPTALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL9244903 | 0.80 | NR4A1 (0.52) | KMT2AMEN1MAPTALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL9244904 | 0.80 | NR4A1 (0.52) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5051397 | 0.79 | SNCA (0.53) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL3497623 | 0.77 | CA12 (0.45) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL3765915 | 0.76 | ANPEP (0.36) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL8928010 | 0.76 | ANPEP (0.36) | KMT2AMEN1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557383-A1 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008456-A2 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1992-05-29 | — | — | WO | disclosed |