SCHEMBL8928038

SCHEMBL8928038

CC1c2ccccc2-c2cccc(C(=O)O)c21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MYC P01106 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.43
HNF4A P41235 1/20 0.43
CDC25B P30305 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GFER P55789 1/20 0.41
CYP2C9 P11712 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
AKR1C3 P42330 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31094256 0.82 ALDH1A1 (0.42) ALDH1A1MYCL3MBTL1LMNAMAPT
SCHEMBL67620 0.81 HNF4A (0.49) ALDH1A1MYCL3MBTL1LMNAMAPT
SCHEMBL3720120 0.79 ALDH1A1 (0.46) ALDH1A1MYCL3MBTL1LMNAMAPT
Dimethylamine SCHEMBL28738763 0.79 HNF4A (0.44) ALDH1A1MYCL3MBTL1LMNAMAPT
SCHEMBL24589717 0.78 FOLH1 (0.39) ALDH1A1MYCL3MBTL1LMNAMAPT
Bicarbonate SCHEMBL4820941 0.77 HTR7 (0.50) LMNAMAPTKMT2AMEN1POLB
SCHEMBL28482428 0.77 HNF4A (0.45) ALDH1A1MYCL3MBTL1LMNAMAPT
SCHEMBL11570150 0.76 AKR1B1 (0.44) MAPTCYP2C9POLBFOLH1
SCHEMBL18063291 0.75 MAPK1 (0.43) ALDH1A1MYCL3MBTL1LMNAMAPT
SCHEMBL7796836 0.74 CYP2C9 (0.49) ALDH1A1MYCL3MBTL1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US disclosed