Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14487736 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1HSD17B10KDM4ECYP2C19SMN1; SMN2 | |
| SCHEMBL3733939 | 0.79 | CASP1 (0.34) | KMT2APOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL8928043 | 0.78 | CYP26A1 (0.43) | CYP26A1ALPLALPGALPIPLAA | |
| SCHEMBL10688674 | 0.77 | ALDH1A1 (0.44) | CYP26A1ALDH1A1KDM4EMAPTFDPS | |
| SCHEMBL8741557 | 0.76 | LMNA (0.43) | KMT2AALDH1A1MEN1MAPTCYP2C19 | |
| SCHEMBL3932075 | 0.74 | KMT2A (0.40) | CYP26A1KMT2APOLBALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL10364074 | 0.74 | CYP26A1 (0.38) | CYP26A1ALDH1A1KDM4EFDPSHTT | |
| SCHEMBL18250722 | 0.74 | ALDH1A1 (0.42) | CYP26A1KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL2932043 | 0.72 | KMT2A (0.41) | CYP26A1KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL2797959 | 0.71 | L3MBTL1 (0.45) | CYP26A1KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |