Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928078 | 0.96 | MTNR1A (0.65) | MTNR1AMTNR1BPKM | |
| SCHEMBL8928075 | 0.91 | MTNR1A (0.62) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8928250 | 0.91 | MTNR1A (0.62) | MTNR1AMTNR1BPKMALDH1A1 | |
| SCHEMBL8928118 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8928104 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL13725463 | 0.82 | MTNR1A (0.79) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL28850813 | 0.81 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL29991337 | 0.81 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL8928239 | 0.81 | KMT2A (0.65) | ALDH1A1 | |
| SCHEMBL8928085 | 0.80 | MTNR1A (0.75) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | claimed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | claimed |
| JP-8176080-A | — | — | None | — | — | JP | disclosed |
| WO-1997048701-A1 | 4,1-BENZOXAZEPINES OR 4,1-BENZOTHIAZEPINES AND THEIR USE AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| JP-H08176080-A | NEW MELATONERGIC AGENT | BRISTOL MYERS SQUIBB CO | 1996-07-09 | — | — | JP | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |