Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | BRD2 | P25440 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928684 | 0.91 | PTAFR (0.45) | OPRK1PTAFR | |
| SCHEMBL8928371 | 0.86 | HPGD (0.45) | HPGDSMN1; SMN2RECQLBRD4KDM4E | |
| SCHEMBL8928425 | 0.84 | MAPK1 (0.44) | HPGDSMN1; SMN2RECQLBRD4BRD2 | |
| SCHEMBL8928569 | 0.83 | OPRK1 (0.51) | HPGDSMN1; SMN2RECQLBRD4KDM4E | |
| SCHEMBL8928488 | 0.83 | HPGD (0.44) | HPGDSMN1; SMN2RECQLBRD4KDM4E | |
| SCHEMBL8928636 | 0.81 | MIF (0.44) | BRD4KDM4EOPRK1 | |
| SCHEMBL8928900 | 0.80 | PTAFR (0.51) | OPRK1PTAFR | |
| SCHEMBL8928520 | 0.79 | HPGD (0.41) | HPGDSMN1; SMN2RECQLBRD4KDM4E | |
| SCHEMBL8928876 | 0.79 | MEN1 (0.37) | HPGDSMN1; SMN2RECQLBRD4BRD2 | |
| SCHEMBL8928620 | 0.79 | SMN1; SMN2 (0.40) | HPGDSMN1; SMN2RECQLBRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |