Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | BRD4 | O60885 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | PTAFR | P25105 | 14/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928436 | 0.86 | OPRK1 (0.77) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| SCHEMBL8928433 | 0.85 | PTAFR (0.79) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| SCHEMBL8928600 | 0.85 | OPRK1 (0.47) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| Bicarbonate SCHEMBL10510835 | 0.83 | PTAFR (0.72) | GABRA1GABRA5GABRA2OPRK1GABRA3 | |
| SCHEMBL2442196 | 0.81 | GABRA1 (0.57) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| SCHEMBL9663031 | 0.81 | PTAFR (0.62) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| SCHEMBL7324237 | 0.78 | BRD4 (0.81) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| SCHEMBL9038947 | 0.78 | BRD4 (0.50) | GABRA1GABRA5GABRA2GABRB2OPRK1 | |
| SCHEMBL11509934 | 0.76 | PTAFR (0.79) | GABRA1GABRA5GABRA2OPRK1GABRA3 | |
| SCHEMBL8320646 | 0.75 | BRD4 (0.36) | GABRA1GABRA5GABRA2GABRB2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |