Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 9/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928613 | 0.89 | OPRK1 (0.46) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928633 | 0.87 | OPRK1 (0.58) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928550 | 0.87 | OPRK1 (0.60) | OPRK1GABRA1GABRA5GABRA2GABRA3 | |
| SCHEMBL8928426 | 0.85 | GABRA1 (0.59) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928945 | 0.81 | OPRK1 (0.44) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928450 | 0.80 | OPRK1 (0.40) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL11037044 | 0.77 | OPRK1 (0.56) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928788 | 0.77 | OPRK1 (0.56) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928566 | 0.77 | OPRK1 (0.56) | OPRK1HPGDGABRA1GABRA5GABRA2 | |
| SCHEMBL8928437 | 0.76 | HPGD (0.41) | HPGDRECQLSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |