Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | PTAFR | P25105 | 19/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507032 | 0.91 | OPRK1 (0.57) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL10869413 | 0.85 | OPRK1 (0.90) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928393 | 0.84 | OPRK1 (0.67) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL11077003 | 0.84 | GABRA1 (0.53) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL30665015 | 0.83 | OPRK1 (1.00) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| Etizolam SCHEMBL42920 | 0.83 | OPRK1 (1.00) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928481 | 0.83 | OPRK1 (0.84) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8928449 | 0.81 | OPRK1 (0.80) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL11711904 | 0.81 | OPRK1 (0.57) | OPRK1PDE4DPTAFRCYP3A4ALOX15 | |
| SCHEMBL8878112 | 0.81 | OPRK1 (0.79) | OPRK1PDE4DPTAFRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |