Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928565 | 0.86 | HPGD (0.45) | MAPK1KMT2AHPGDRECQLSMN1; SMN2 | |
| SCHEMBL8928618 | 0.85 | OPRK1 (0.54) | MAPK1KMT2AHPGDRECQLSMN1; SMN2 | |
| SCHEMBL8928425 | 0.83 | MAPK1 (0.44) | MAPK1KMT2AHPGDRECQLSMN1; SMN2 | |
| SCHEMBL8928531 | 0.82 | HPGD (0.41) | HPGDRECQLSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL8928488 | 0.82 | HPGD (0.44) | HPGDRECQLSMN1; SMN2KDM4EOPRK1 | |
| SCHEMBL8928513 | 0.80 | PKM (0.42) | MAPK1KMT2AHPGDRECQLSMN1; SMN2 | |
| SCHEMBL8928406 | 0.80 | OPRK1 (0.53) | MAPK1KMT2AHPGDRECQLSMN1; SMN2 | |
| SCHEMBL8928625 | 0.80 | OPRK1 (0.47) | MAPK1KMT2AOPRK1PTAFR | |
| SCHEMBL8928438 | 0.79 | OPRK1 (0.51) | MAPK1OPRK1PTAFR | |
| SCHEMBL8928456 | 0.78 | OPRK1 (0.63) | OPRK1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |