Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183194 | 0.79 | RAB9A (0.42) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL1800550 | 0.79 | NPC1 (0.42) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL6966557 | 0.79 | RAB9A (0.42) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL6650651 | 0.77 | POLB (0.50) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL7321755 | 0.77 | RAB9A (0.41) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL19769133 | 0.76 | FFAR1 (0.42) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL10846303 | 0.74 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL6964081 | 0.72 | NPC1 (0.39) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL17593665 | 0.69 | NPC1 (0.37) | RAB9ANPC1ALOX5ALDH1A1ALOX12 | |
| SCHEMBL9789298 | 0.66 | RAB9A (0.43) | RAB9ANPC1ALOX5ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693827-A | Treatment of HIV infections and compounds useful therein | UNIROYAL CHEMICAL COMPANY, INC. | 1997-12-02 | — | — | US | disclosed |