Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536849 | 0.71 | BRD4 (0.49) | NPSR1ADORA3KMT2A | |
| SCHEMBL8675772 | 0.66 | EGFR (0.56) | LMNATSHRALDH1A1MAPK1HSD17B10 | |
| SCHEMBL8675770 | 0.66 | NPSR1 (0.42) | NPSR1ADORA3TMIGD3LMNAALDH1A1 | |
| SCHEMBL23283443 | 0.63 | SLC22A12 (0.44) | NPSR1ADORA3TMIGD3LMNATSHR | |
| SCHEMBL29971311 | 0.63 | SLC22A12 (0.44) | NPSR1ADORA3TMIGD3LMNATSHR | |
| SCHEMBL28603035 | 0.62 | KMT2A (0.56) | ADORA3TMIGD3KMT2ALMNATSHR | |
| SCHEMBL9566589 | 0.61 | ADORA3 (0.43) | NPSR1ADORA3TMIGD3KMT2ALMNA | |
| SCHEMBL10937900 | 0.60 | L3MBTL1 (0.53) | NPSR1KMT2ACES2CES1LMNA | |
| SCHEMBL8723486 | 0.60 | KMT2A (0.53) | NPSR1ADORA3TMIGD3KMT2ATSHR | |
| SCHEMBL27685166 | 0.58 | L3MBTL1 (0.50) | NPSR1KMT2ACES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014709-A1 | ANTISENSE OLIGOMERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-04-24 | — | — | WO | disclosed |