Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930635 | 0.89 | GRIN1 (0.36) | GRIN1HTTMEN1KMT2A | |
| SCHEMBL8487399 | 0.81 | GRIN1 (0.40) | GRIN1MEN1KMT2A | |
| SCHEMBL8930335 | 0.80 | GRIN1 (0.38) | GRIN1 | |
| SCHEMBL8485007 | 0.78 | RAB9A (0.48) | GRIN1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8489271 | 0.74 | GRIN1 (0.37) | GRIN1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7471711 | 0.72 | GRIN1 (0.39) | GRIN1KDM4EMAPTALDH1A1 | |
| SCHEMBL8650855 | 0.72 | GRIN1 (0.42) | GRIN1MEN1KMT2A | |
| SCHEMBL7470542 | 0.72 | GRIN1 (0.39) | GRIN1MEN1KMT2A | |
| SCHEMBL7472397 | 0.72 | GRIN1 (0.35) | GRIN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8524581 | 0.72 | MCL1 (0.34) | GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |