SCHEMBL8930343

SCHEMBL8930343

O=C(O)Cc1cccc(S(=O)(=O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.52
TSHR P16473 4/20 0.48
HSD17B10 Q99714 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PTGDR2 Q9Y5Y4 3/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
RGS12 O14924 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
NFKB1 P19838 1/20 0.44
APEX1 P27695 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetic Acid SCHEMBL28238677 0.85 AKR1B1 (0.68) AKR1B1TSHRALDH1A1SMN1; SMN2LMNA
SCHEMBL335277 0.84 ALDH1A1 (0.54) AKR1B1HSD17B10ALDH1A1SMN1; SMN2PTGDR2
SCHEMBL4137892 0.84 AKR1B1 (0.50) AKR1B1TSHRHSD17B10TDP1ALDH1A1
SCHEMBL4026429 0.84 CA1 (0.55) AKR1B1TSHRHSD17B10TDP1CYP1A2
SCHEMBL14033126 0.84 HTR6 (0.60) AKR1B1TSHRPTGDR2CYP1A2CYP2C19
SCHEMBL167735 0.82 PSIP1 (0.52) AKR1B1TSHRHSD17B10TDP1ALDH1A1
SCHEMBL13941255 0.81 AKR1B1 (0.47) AKR1B1TSHRHSD17B10TDP1ALDH1A1
SCHEMBL3468833 0.81 AKR1B1 (0.47) AKR1B1TSHRHSD17B10TDP1ALDH1A1
SCHEMBL21726593 0.80 TSHR (0.55) TSHRHSD17B10TDP1ALDH1A1SMN1; SMN2
SCHEMBL16799940 0.80 AKR1B1 (0.46) AKR1B1TSHRHSD17B10TDP1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230194537-A1 COMPOUNDS FOR THE DETECTION OF GLYCANS Life Technologies Corporation 2023-06-22 US disclosed
CN-114026427-A Marker for diagnosing renal disease and diagnostic method 深圳市中医院 2022-02-08 CN disclosed
CN-109970920-B Sulfonic acid modified polycarboxylic acid water reducing agent and preparation method thereof 科之杰新材料集团有限公司 2020-07-03 CN disclosed
EP-3218328-A1 MULTI - LIGAND PREPARATIONS CONTAINING ONE OR MORE METAL SPECIES Future Tense Technological Development & Entrepreneurship Ltd. (IL) 2017-09-20 EP disclosed
WO-2016075685-A1 MULTI - LIGAND PREPARATIONS CONTAINING ONE OR MORE METAL SPECIES FUTURE TENSE TECHNOLOGICAL DEVELOPMENT & ENTREPRENEURSHIP LTD (IL) 2016-05-19 WO disclosed
US-5665150-A Dye and ink compositions XEROX CORPORATION (US) 1997-09-09 US disclosed