Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.60 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | HRH2 | P25021 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930455 | 0.86 | HRH4 (0.66) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL8930459 | 0.76 | HRH4 (0.49) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL167601 | 0.75 | DRD2 (0.74) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL29969899 | 0.75 | DRD2 (0.74) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL140907 | 0.75 | HRH4 (1.00) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL11480248 | 0.75 | HRH4 (0.73) | HRH4DRD2DRD4DRD3HRH2 | |
| Hydrochloric Acid SCHEMBL5606161 | 0.74 | HRH4 (0.97) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL172210 | 0.74 | HRH4 (0.65) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL7256287 | 0.72 | HRH4 (0.76) | HRH4DRD2DRD4DRD3HRH2 | |
| SCHEMBL7249840 | 0.72 | HRH4 (0.72) | HRH4DRD2DRD4DRD3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602124-A | ANTISEROTONINE AGENT | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1997-02-11 | — | — | US | disclosed |
| WO-1996018629-A1 | 5-HT2 RECEPTOR LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (US) | 1996-06-20 | — | — | WO | disclosed |