Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.74 |
| ▸ | HRH1 | P35367 | 4/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.74 |
| ▸ | HTR2A | P28223 | 4/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.74 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.74 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.74 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.74 |
| ▸ | DRD1 | P21728 | 4/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.74 |
| ▸ | DRD4 | P21917 | 4/20 | 0.74 |
| ▸ | DRD3 | P35462 | 4/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.74 |
| ▸ | HRH2 | P25021 | 3/20 | 0.74 |
| ▸ | HTR1A | P08908 | 3/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.74 |
| ▸ | HTR2C | P28335 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167601 | 1.00 | DRD2 (0.74) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| SCHEMBL3409689 | 0.87 | DRD2 (0.80) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| Amoxapine SCHEMBL33950 | 0.85 | DRD2 (1.00) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| Amoxapine SCHEMBL29354942 | 0.85 | DRD2 (1.00) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| Amoxapine SCHEMBL29482386 | 0.85 | DRD2 (1.00) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| SCHEMBL2738976 | 0.85 | DRD4 (0.82) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| SCHEMBL2615197 | 0.85 | DRD2 (0.74) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| SCHEMBL3411889 | 0.85 | DRD2 (0.74) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| SCHEMBL3405535 | 0.85 | DRD2 (0.63) | DRD2CHRM1HRH1ADRA2AHTR2A | |
| Amoxapine SCHEMBL29370074 | 0.85 | DRD2 (1.00) | DRD2CHRM1HRH1ADRA2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-08-19 | — | — | US | disclosed |
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | GRB2, SCTR, OGFR | DRD2 2137/4885CHRM1 1197/4885HRH1 316/4885 |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | QSOX1, YBX1, SFXN1 | DRD2 3192/4885CHRM1 364/4885HRH1 3335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.