SCHEMBL8930599

SCHEMBL8930599

CC(=O)N(c1ccc(N=C=S)cc1)N1CCNCCNCCNCC1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALOX12 P18054 1/20 0.34
OPRD1 P41143 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PNMT P11086 1/20 0.33
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
P2RY6 Q15077 1/20 0.31
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719314 0.79 HSD17B10 (0.39) TP53CYP1A2CYP3A4CYP2D6ALOX12
SCHEMBL8930521 0.78 GFER (0.36) TP53CYP1A2CYP3A4CYP2D6OPRD1
SCHEMBL5717885 0.76 SIGMAR1 (0.45) OPRD1HSD17B10
Hydrochloric Acid SCHEMBL5849112 0.75 SIGMAR1 (0.44) OPRD1HSD17B10
SCHEMBL8930545 0.74 ADRB1 (0.49) CYP1A2CYP3A4CYP2D6
SCHEMBL7544912 0.70 CYP4A11 (0.38) CA2
SCHEMBL7536787 0.70 FFAR1 (0.41) HSD17B10CA1CA2
SCHEMBL12555569 0.70 SMN1; SMN2 (0.45) HSD17B10CA1CA2P2RY6MIF
SCHEMBL7538929 0.69 AOC3 (0.37)
SCHEMBL7536716 0.69 KMT2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997014443-A1 MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES BRACCO INTERNATIONAL B.V. (NL) 1997-04-24 WO disclosed