SCHEMBL8930607

SCHEMBL8930607

Fc1ccc(C(Cl)c2cnc(C(F)F)nc2Cl)cc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 1/20 0.32
HDAC6 Q9UBN7 8/20 0.31
TBXA2R P21731 1/20 0.31
PTGDR Q13258 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
RXRA P19793 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930549 0.89 TSHR (0.33) FFAR2
SCHEMBL8930616 0.77 IDO1 (0.33) FFAR2HDAC6
SCHEMBL8930608 0.72 HPGD (0.35) FFAR2HDAC6
SCHEMBL26598773 0.69
SCHEMBL8930575 0.69 CYP19A1 (0.33)
SCHEMBL8566402 0.68 APLNR (0.33)
SCHEMBL424538 0.66 IDO1 (0.46) HDAC6
SCHEMBL8930564 0.66 IDO1 (0.32)
SCHEMBL8176734 0.65 POLB (0.36)
SCHEMBL8561982 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764641-A1 NOVEL 4,5-DISUBSTITUTED PYRIMIDINE DERIVATIVE AND HERBICIDE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-03-26 EP disclosed
CN-1133589-A Novel pyrimidine derivative, herbicide and plant growth regulator NISSAN CHEMICAL IND LTD (JP) 1996-10-16 CN disclosed