Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 6/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL28479522 | 0.88 | LMNA (0.40) | LMNAALOX15PAOXALDH1A1MEN1 | |
| Diethanolamine SCHEMBL8571462 | 0.88 | ALDH1A1 (0.40) | LMNAALOX15BLMPMP22ALDH1A1 | |
| Diethanolamine SCHEMBL9790976 | 0.85 | FFAR3 (0.44) | LMNAPAOXALDH1A1MEN1USP2 | |
| Diethanolamine SCHEMBL502768 | 0.85 | FFAR3 (0.44) | LMNAPAOXALDH1A1MEN1USP2 | |
| Diethanolamine SCHEMBL9588654 | 0.85 | ACHE (0.44) | LMNAPAOXALDH1A1MEN1USP2 | |
| Diethanolamine SCHEMBL10469515 | 0.85 | MEN1 (0.36) | LMNAALOX15BLMPMP22ALDH1A1 | |
| Diethanolamine SCHEMBL9587569 | 0.83 | ALDH1A1 (0.38) | LMNAALOX15ALDH1A1MEN1USP2 | |
| Diethanolamine SCHEMBL27444292 | 0.83 | MEN1 (0.33) | ALOX15PAOXALDH1A1MEN1USP2 | |
| Diethanolamine SCHEMBL11454426 | 0.82 | FFAR3 (0.41) | LMNAPAOXALDH1A1MEN1USP2 | |
| Diethanolamine SCHEMBL3630770 | 0.82 | FFAR3 (0.41) | LMNAPAOXALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042739-C | Fatty acid hydroxyalkylamides as coreactable stabilizers and flow aids for powder coatings | ROHM & HAAS (US) | 1999-03-31 | — | — | CN | claimed |
| EP-0582363-B1 | A thermosetting powder coating composition | INVENTA AG (CH) | 1997-06-04 | — | — | EP | claimed |
| US-5346960-A | Reactable mixture of carboxy acid containing acrylic, beta-hydroxyalkylamide curative and fatty acid hydroxyalkylamide; industrial metal coatings | ROHM AND HAAS COMPANY (US) | 1994-09-13 | — | — | US | claimed |
| EP-0582363-A1 | A thermosetting powder coating composition | ROHM AND HAAS COMPANY (US) | 1994-02-09 | — | — | EP | claimed |
| CN-1081699-A | But the lipid acid hydroxyalkyl amide is as the stablizer of the coreaction of powder coating | ROHM & HAAS (US) | 1994-02-09 | — | — | CN | claimed |
| US-5216090-A | Fatty acid hydroxyalkylamides as coreactable stabilizers and flow aids for powder coatings | ROHM AND HAAS COMPANY (US) | 1993-06-01 | — | — | US | claimed |
| CN-1118528-C | Soap gel based glue stick | HENKEL KGAA (DE) | 2003-08-20 | — | — | CN | disclosed |
| CN-1295603-A | Soap gel based glue stick | HENKEL KGAA (DE) | 2001-05-16 | — | — | CN | disclosed |
| CN-1042739-C | Fatty acid hydroxyalkylamides as coreactable stabilizers and flow aids for powder coatings | ROHM & HAAS (US) | 1999-03-31 | — | — | CN | disclosed |
| EP-0582363-B1 | A thermosetting powder coating composition | INVENTA AG (CH) | 1997-06-04 | — | — | EP | disclosed |
| US-5346960-A | Reactable mixture of carboxy acid containing acrylic, beta-hydroxyalkylamide curative and fatty acid hydroxyalkylamide; industrial metal coatings | ROHM AND HAAS COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0582363-A1 | A thermosetting powder coating composition | ROHM AND HAAS COMPANY (US) | 1994-02-09 | — | — | EP | disclosed |
| CN-1081699-A | But the lipid acid hydroxyalkyl amide is as the stablizer of the coreaction of powder coating | ROHM & HAAS (US) | 1994-02-09 | — | — | CN | disclosed |
| US-5216090-A | Fatty acid hydroxyalkylamides as coreactable stabilizers and flow aids for powder coatings | ROHM AND HAAS COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0056145-B1 | PROCESS FOR THE PRODUCTION OF INORGANIC-ORGANIC FOAMS | Mobay Chemical Corporation (US) | 1985-06-12 | — | — | EP | disclosed |
| US-4355118-A | POLYISOCYANATE, ALKALIMETAL SILICATE, ONIUM COMPOUND | MOBAY CHEMICAL CORPORATION (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0056145-A1 | Process for the production of inorganic-organic foams | Mobay Chemical Corporation (US) | 1982-07-21 | — | — | EP | disclosed |