Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL27879356 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| Diethanolamine SCHEMBL8931210 | 0.83 | LMNA (0.47) | MEN1KMT2APAOXALDH1A1USP2 | |
| Diethanolamine SCHEMBL8571462 | 0.83 | ALDH1A1 (0.40) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| Diethanolamine SCHEMBL1830524 | 0.81 | FFAR3 (0.56) | MEN1KMT2APAOXALDH1A1USP2 | |
| Diethanolamine SCHEMBL29213589 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2APAOXALDH1A1USP2 | |
| Diethanolamine SCHEMBL29148402 | 0.81 | FFAR3 (0.56) | MEN1KMT2APAOXALDH1A1USP2 | |
| Diethanolamine SCHEMBL9588654 | 0.80 | ACHE (0.44) | MEN1KMT2APAOXMAOAMAOB | |
| Diethanolamine SCHEMBL10469515 | 0.80 | MEN1 (0.36) | MEN1KMT2AMAOAMAOBALDH1A1 | |
| Propionamide SCHEMBL15155215 | 0.80 | — | — | |
| SCHEMBL3134640 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118528-C | Soap gel based glue stick | HENKEL KGAA (DE) | 2003-08-20 | — | — | CN | disclosed |
| CN-1295603-A | Soap gel based glue stick | HENKEL KGAA (DE) | 2001-05-16 | — | — | CN | disclosed |