Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL7137485 | 0.94 | POLB (0.38) | HDAC4EP300MEF2DHDAC1HDAC2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8549018 | 0.81 | MAPT (0.34) | ALDH1A1MAPTUSP2LMNAHTT | |
| Trifluoromethanesulfonic Acid SCHEMBL8194433 | 0.70 | HSP90AA1 (0.40) | MAPTKMT2APOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL8189875 | 0.67 | HTR1F (0.56) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1885467 | 0.62 | HDAC1 (0.65) | HDAC4EP300MEF2DHDAC1HDAC2 | |
| SCHEMBL240595 | 0.61 | SMN1; SMN2 (0.75) | ALDH1A1MAPTHDAC6HTTSMN1; SMN2 | |
| SCHEMBL31484185 | 0.61 | SMN1; SMN2 (0.75) | ALDH1A1MAPTHDAC6HTTSMN1; SMN2 | |
| SCHEMBL4237754 | 0.59 | GRIN1 (0.54) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13013631 | 0.58 | SPR (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21709938 | 0.58 | LMNA (0.67) | ALDH1A1MAPTKMT2AKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013512-A1 | N-[2-SUBSTITUTED-3-(2-AMINOETHYL)-1H-INDOL-5-YL]-AMIDES: NEW 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |