Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931362 | 0.81 | — | — | |
| SCHEMBL8931364 | 0.80 | ALDH1A1 (0.37) | CYP1A2HRH2HRH1HRH4 | |
| SCHEMBL27748701 | 0.72 | — | — | |
| SCHEMBL8931338 | 0.71 | CYP1A2 (0.44) | CYP1A2HRH2HRH1HRH4 | |
| SCHEMBL8931394 | 0.68 | — | — | |
| SCHEMBL25479146 | 0.66 | — | — | |
| SCHEMBL8931349 | 0.64 | ALDH1A1 (0.55) | CYP1A2 | |
| SCHEMBL10082423 | 0.64 | FBP1 (0.41) | CYP1A2HRH2HRH1HRH4 | |
| SCHEMBL5154036 | 0.63 | — | — | |
| SCHEMBL2614500 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648498-A | Process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof | ASTRA AKTIEBOLAG (SE) | 1997-07-15 | — | — | US | disclosed |
| EP-0546306-B1 | 5-(2-Chloroalkyl)-4-methylthiazoles, their preparation and their use, and intermediates for their preparation | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0619815-B1 | PROCESS FOR THE PREPARATION OF 4-METHYL-5-(2-CHLOROETHYL)-THIAZOLE AND ANALOGUES THEREOF | ASTRA AB (SE) | 1997-04-16 | — | — | EP | disclosed |
| US-5534644-A | Process for the preparation of 4-methyl-5-(2-chloroethyl)-thiazole and analogues thereof | AKTIEBOLAGET ASTRA (SE) | 1996-07-09 | — | — | US | disclosed |
| EP-0619815-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-METHYL-5-(2-CHLOROETHYL)-THIAZOLE AND ANALOGUES THEREOF. | ASTRA AB (SE) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993009107-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-METHYL-5-(2-CHLOROETHYL)-THIAZOLE AND ANALOGUES THEREOF | AKTIEBOLAGET ASTRA (SE) | 1993-05-13 | — | — | WO | disclosed |