SCHEMBL8931480

SCHEMBL8931480

CC(C)C1CC2=Cc3cccc4cccc(c34)C21

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27784871 0.68 MEN1 (0.33) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL27272521 0.67 MEN1 (0.32) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL25227489 0.66 MEN1 (0.36) MEN1ALDH1A1MAPTKMT2A
SCHEMBL1664601 0.66 ADRA2A (0.40) MEN1ALDH1A1MAPTKMT2A
SCHEMBL10633942 0.64 MTNR1A (0.44) KDM4E
Carbimide SCHEMBL27416811 0.63 MEN1 (0.31) MEN1MAPTKMT2A
SCHEMBL28070297 0.62 ALDH1A1 (0.33) KDM4EMEN1ALDH1A1POLBMAPT
SCHEMBL1664607 0.61 MEN1 (0.34) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL28281441 0.61
Water SCHEMBL3478610 0.60 MEN1 (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638107-B1 ANTI-FATIQUE COAGENTS FOR RUBBER VULCANIZATION AKZO NOBEL NV (NL) 1997-05-14 EP claimed