Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.30 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.30 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830788 | 0.86 | TK1 (0.32) | — | |
| SCHEMBL8932105 | 0.86 | PLA2G2A (0.32) | ALDH1A1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL8931932 | 0.85 | — | — | |
| SCHEMBL8931951 | 0.83 | — | — | |
| SCHEMBL8931999 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8931981 | 0.82 | — | — | |
| SCHEMBL8932064 | 0.82 | FPR1 (0.32) | — | |
| SCHEMBL8932126 | 0.80 | NQO2 (0.31) | — | |
| SCHEMBL8932077 | 0.77 | TK1 (0.36) | — | |
| SCHEMBL6829895 | 0.76 | TK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681940-A | CONTAIN TETRAHYDROTHIOPHENE OR PYROLIDINE RINGS | ICN PHARMACEUTICALS (US) | 1997-10-28 | — | — | US | disclosed |