Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931961 | 0.77 | AGTR1 (0.39) | APAF1LTB4R2ALDH1A1 | |
| SCHEMBL8931904 | 0.67 | AGTR1 (0.41) | LTB4R2 | |
| SCHEMBL8931850 | 0.67 | AGTR1 (0.41) | LTB4R2 | |
| SCHEMBL8931810 | 0.66 | AGTR1 (0.41) | ASAH1LTB4R2 | |
| SCHEMBL8931908 | 0.64 | AGTR1 (0.39) | KMT2ALTB4R2CYP3A4ALDH1A1 | |
| SCHEMBL29145169 | 0.60 | KMT2A (0.54) | ALOX15HSD17B10MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29145145 | 0.59 | SMN1; SMN2 (0.49) | HSD17B10APAF1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10504076 | 0.59 | ASAH1 (0.50) | HSD17B10APAF1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10504808 | 0.59 | ASAH1 (0.47) | HSD17B10APAF1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL14268957 | 0.59 | ALDH1A1 (0.47) | HSD17B10APAF1MAPTKDM4EASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |