Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 8/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932086 | 0.72 | ACHE (0.46) | ACHECES1CES2HDAC4HDAC6 | |
| SCHEMBL856445 | 0.67 | — | — | |
| SCHEMBL30608294 | 0.67 | — | — | |
| SCHEMBL8932112 | 0.67 | ACHE (0.56) | ACHECES1CES2HDAC4HDAC6 | |
| SCHEMBL10014737 | 0.66 | AKR1C3 (0.48) | ACHEHDAC4HDAC6DHODH | |
| SCHEMBL7004078 | 0.66 | CES1 (0.36) | CES1CES2HDAC6 | |
| SCHEMBL27318018 | 0.66 | ACHE (0.46) | ACHECES1MLYCDHDAC4HDAC6 | |
| SCHEMBL8861678 | 0.66 | ACHE (0.54) | ACHECES1MLYCD | |
| SCHEMBL25257484 | 0.63 | AR (0.36) | ACHECES1MLYCD | |
| SCHEMBL953002 | 0.63 | CES1 (0.39) | CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684951-B1 | SILYLATED ACETYLCHOLINESTERASE INHIBITORS | MERRELL PHARMA INC (US) | 1997-05-07 | — | — | EP | claimed |