SCHEMBL8932224

SCHEMBL8932224

COC(F)(F)C(C)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22007749 0.81 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17126848 0.77
SCHEMBL648319 0.76
SCHEMBL9587715 0.75
SCHEMBL9931 0.74
SCHEMBL4578155 0.73 ALDH1A1 (0.39) ALDH1A1
SCHEMBL24759170 0.72
SCHEMBL7642854 0.72
SCHEMBL422693 0.72
SCHEMBL14213167 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3830176-B1 COMPOSITION, FOAMED SILICONE ELASTOMER FORMED THEREFROM, AND METHODS OF FORMATION DOW SILICONES CORP (US) 2024-01-24 EP disclosed
US-11820912-B2 Fluoropolyether group-containing polymer-modified organic silicon compound, surface treatment agent, and article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
CN-116917029-A Microparticles and microparticle dispersions 国立大学法人东京大学 2023-10-20 CN disclosed
US-20230331923-A1 COMPOSITION, SILICONE POLYETHER SURFACTANT FORMED THEREFROM, AND RELATED METHODS AND ARTICLES DOW SILICONES CORPORATION 2023-10-19 US disclosed
US-20230331923-A1 COMPOSITION, SILICONE POLYETHER SURFACTANT FORMED THEREFROM, AND RELATED METHODS AND ARTICLES DOW SILICONES CORPORATION 2023-10-19 US disclosed
US-20230302491-A1 METHOD FOR THE IN-SITU ENCAPSULATION AND/OR INSULATION OF PIPING DOW GLOBAL TECHNOLOGIES LLC 2023-09-28 US disclosed
US-20230250216-A1 COMPOSITION AND FOAMED POLYURETHANE ARTICLE FORMED THEREWITH DOW SILICONES CORPORATION 2023-08-10 US disclosed
US-20230219342-A1 WATER-REPELLENT MEMBER, INKJET HEAD, METHOD OF MANUFACTURING WATER-REPELLENT MEMBER, AND METHOD OF MANUFACTURING INKJET HEAD CANON KABUSHIKI KAISHA (JP) 2023-07-13 US disclosed
US-20230193102-A1 HIGH TEMPERATURE LOW OUTGAS FLUORINATED THERMAL INTERFACE MATERIAL DAIKIN AMERICA, INC. (US) 2023-06-22 US disclosed
US-11664536-B2 Electrolytes for lithium batteries with carbon and/or silicon anodes BATTELLE MEMORIAL INSTITUTE (US) 2023-05-30 US disclosed
WO-2021158579-A1 THE PREPARATION OF FOAMED SILICONE ELASTOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-08-12 WO disclosed
WO-2020028299-A1 COMPOSITION, FOAMED SILICONE ELASTOMER FORMED THEREFROM, AND METHODS OF FORMATION DOW SILICONES CORPORATION (US) 2020-02-06 WO disclosed
US-10035812-B2 Perfluoropolyether-modified polysilazane, making method, surface treating agent, and treated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-07-31 US disclosed
WO-2018136324-A1 FLUORINATED BLOCK COPOLYMERS DERIVED FROM NITRILE CURE-SITE MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-07-26 WO disclosed
US-9490111-B2 Microdroplet ionisation mass spectrometry CAMBRIDGE ENTERPRISE LIMITED (GB) 2016-11-08 US disclosed
US-20150274870-A1 PERFLUOROALKYLENE ETHER-CONTAINING COMPOUND AND SURFACE PROTECTIVE FILM FUJI XEROX CO., LTD. (JP) 2015-10-01 US disclosed
US-20130187040-A1 IONISATION MASS SPECTROMETRY CAMBRIDGE ENTERPRISE LIMITED (GB) 2013-07-25 US disclosed
US-8187732-B2 Media lubricant for high temperature application SEAGATE TECHNOLOGY LLC (US) 2012-05-29 US disclosed
US-20120037800-A1 PERFORMANCE EVALUATION METHOD WITH X-RAY AND ITS USAGE HOYA LENS THAILAND LTD. (TH) 2012-02-16 US disclosed
US-20110117386-A1 MEDIA LUBRICANT FOR HIGH TEMPERATURE APPLICATION SEAGATE TECHNOLOGY LLC (US) 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10035812-B2 Perfluoropolyether-modified polysilazane, making method, surface treating agent, and treated article FLNA, SPOP, POLL ALDH1A1 2266/4885
US-20150274870-A1 PERFLUOROALKYLENE ETHER-CONTAINING COMPOUND AND SURFACE PROTECTIVE FILM F11, F12, F8 ALDH1A1 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.