SCHEMBL8932240

SCHEMBL8932240

CCOC=C(C(=O)OC)C(=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26005755 1.00 ALDH1A1 (0.33) ALDH1A1MAPTNPSR1
SCHEMBL18936274 1.00 ALDH1A1 (0.33) ALDH1A1MAPTNPSR1
SCHEMBL18936278 0.86 NPSR1 (0.30) NPSR1
SCHEMBL965898 0.86 NPSR1 (0.30) NPSR1
SCHEMBL18936279 0.86 NPSR1 (0.30) NPSR1
SCHEMBL5188862 0.86 NPSR1 (0.44) ALDH1A1MAPTNPSR1
SCHEMBL251634 0.86 NPSR1 (0.44) ALDH1A1MAPTNPSR1
SCHEMBL215091 0.86 NPSR1 (0.44) ALDH1A1MAPTNPSR1
SCHEMBL2335326 0.82 NPSR1 (0.35) ALDH1A1NPSR1
SCHEMBL1336751 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2257532-B1 METHOD FOR REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-1-PYRAZOL-4-CARBONIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2013-05-29 EP claimed
EP-3178813-A1 METHOD FOR PREPARING HALOGENATED 3-OXOCARBOXYLATES CARRYING A 2-ALKOXYMETHYLIDENE OR A 2-DIALKYLAMINOMETHYLIDENE GROUP BASF SE (DE) 2017-06-14 EP disclosed
US-5498624-A PLANT FUNGICIDES MONSANTO COMPANY (US) 1996-03-12 US disclosed