Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932240 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL18936274 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL18936278 | 0.86 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL965898 | 0.86 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL18936279 | 0.86 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL5188862 | 0.86 | NPSR1 (0.44) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL251634 | 0.86 | NPSR1 (0.44) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL215091 | 0.86 | NPSR1 (0.44) | ALDH1A1MAPTNPSR1 | |
| SCHEMBL2335326 | 0.82 | NPSR1 (0.35) | ALDH1A1NPSR1 | |
| SCHEMBL1336751 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265068-A1 | TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265068-A1 | TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 INHIBITORS AND METHODS OF USE THEREOF | TRPC3, TRPV3, TRPV1 | ALDH1A1 3563/4885MAPT 2823/4885NPSR1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.