Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932240 | 0.86 | ALDH1A1 (0.33) | NPSR1 | |
| SCHEMBL18936274 | 0.86 | ALDH1A1 (0.33) | NPSR1 | |
| SCHEMBL26005755 | 0.86 | ALDH1A1 (0.33) | NPSR1 | |
| SCHEMBL18936279 | 0.83 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL18936278 | 0.83 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL2335326 | 0.80 | NPSR1 (0.35) | NPSR1 | |
| SCHEMBL13943351 | 0.74 | ALDH1A1 (0.32) | NPSR1 | |
| SCHEMBL11650327 | 0.74 | GLO1 (0.45) | NPSR1 | |
| SCHEMBL11650330 | 0.74 | GLO1 (0.45) | NPSR1 | |
| SCHEMBL18936344 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257532-B1 | METHOD FOR REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-1-PYRAZOL-4-CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-05-29 | — | — | EP | claimed |
| US-20110028735-A1 | Process for the Regioselective Preparation of 1-Alkyl-3-haloalkylpyrazole-4-carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | claimed |
| US-20110009642-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | claimed |
| EP-2257532-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF L-ALKYL-3-HALOALKYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-12-08 | — | — | EP | claimed |
| EP-2247577-A2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL PYROAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-10 | — | — | EP | claimed |
| EP-2133341-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | claimed |
| WO-2009112157-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF L-ALKYL-3-HALOALKYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-09-17 | — | — | WO | claimed |
| EP-2100883-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-09-16 | — | — | EP | claimed |
| WO-2009106230-A2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL–PYROAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTENGESELLSCHAFT (DE) | 2009-09-03 | — | — | WO | claimed |
| EP-2114855-B1 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | BAYER IP GMBH (DE) | 2016-07-27 | — | — | EP | disclosed |
| EP-2257532-B1 | METHOD FOR REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-1-PYRAZOL-4-CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-8044231-B2 | Method for producing dihalo acetoacetic alkyl esters | BAYER CROPSCIENCE AG (DE) | 2011-10-25 | — | — | US | disclosed |
| US-7939673-B2 | Process for preparing 3-dihalomethyl-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| US-20110028735-A1 | Process for the Regioselective Preparation of 1-Alkyl-3-haloalkylpyrazole-4-carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | disclosed |
| EP-2133341-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2009112157-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF L-ALKYL-3-HALOALKYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-09-17 | — | — | WO | disclosed |
| EP-2100883-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009106230-A2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL–PYROAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTENGESELLSCHAFT (DE) | 2009-09-03 | — | — | WO | disclosed |
| EP-2057126-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028735-A1 | Process for the Regioselective Preparation of 1-Alkyl-3-haloalkylpyrazole-4-carboxylic Acid Derivatives | HCAR3, AADAC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | NPSR1 2679/4885 |
| US-20110009642-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic Acid Derivatives | ATL3, HCAR3, AADAC | NPSR1 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.