Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932257 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL8932318 | 0.71 | PKM (0.43) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL8932234 | 0.70 | KMT2A (0.49) | KMT2AMAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL8932271 | 0.66 | KMT2A (0.39) | KMT2AHDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL8325428 | 0.64 | MAPT (0.36) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL26664506 | 0.64 | PKM (0.42) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL8952165 | 0.64 | PKM (0.46) | MAPTNPSR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9005068 | 0.63 | CYP11B1 (0.38) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8932259 | 0.63 | PTGS1 (0.32) | — | |
| SCHEMBL8932265 | 0.63 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |