Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721706 | 1.00 | POLB (0.44) | POLBGAARAB9ATSHRITGB3 | |
| SCHEMBL7308755 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BMEN1ALDH1A1LMNA | |
| SCHEMBL2419128 | 0.85 | ALDH1A1 (0.56) | TSHRITGB3ITGA2BCYP3A4MEN1 | |
| SCHEMBL2861260 | 0.85 | ALDH1A1 (0.56) | TSHRITGB3ITGA2BCYP3A4MEN1 | |
| SCHEMBL3648356 | 0.85 | POLB (0.38) | POLBGAARAB9AITGB3ITGA2B | |
| SCHEMBL864694 | 0.84 | KLK5 (0.53) | ITGB3ITGA2BACEMEN1ALDH1A1 | |
| SCHEMBL1819934 | 0.84 | KLK5 (0.53) | ITGB3ITGA2BACEMEN1ALDH1A1 | |
| SCHEMBL7442384 | 0.84 | KLK5 (0.53) | ITGB3ITGA2BACEMEN1ALDH1A1 | |
| SCHEMBL2854766 | 0.84 | ALDH1A1 (0.46) | GAARAB9ATSHRITGB3ITGA2B | |
| SCHEMBL2854764 | 0.84 | ALDH1A1 (0.46) | GAARAB9ATSHRITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |