Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866586 | 0.91 | P2RX7 (0.53) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL2866584 | 0.91 | P2RX7 (0.53) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL30229545 | 0.91 | ALDH1A1 (0.54) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL2419128 | 0.89 | ALDH1A1 (0.56) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL2861260 | 0.89 | ALDH1A1 (0.56) | ITGB3ITGA2BCTSLCTSSCTSK | |
| SCHEMBL8932447 | 0.87 | POLB (0.44) | ITGB3ITGA2BMEN1ALDH1A1LMNA | |
| SCHEMBL1721706 | 0.87 | POLB (0.44) | ITGB3ITGA2BMEN1ALDH1A1LMNA | |
| SCHEMBL7318182 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BP2RX7KDM4EMEN1 | |
| SCHEMBL15020052 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BP2RX7KDM4EMEN1 | |
| SCHEMBL2861161 | 0.86 | P2RX7 (0.59) | ITGB3ITGA2BCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643072-B1 | 2-Piperazinone compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-02-24 | — | — | EP | disclosed |
| US-5550131-A | ANTITHROMBOTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0643072-A1 | 2-Piperazinone compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |