Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419128 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ALOX15ITGB3ITGA2BP2RX7 | |
| SCHEMBL30229545 | 0.93 | ALDH1A1 (0.54) | ALDH1A1ALOX15ITGB3ITGA2BP2RX7 | |
| SCHEMBL2866584 | 0.92 | P2RX7 (0.53) | ALDH1A1ALOX15ITGB3ITGA2BP2RX7 | |
| SCHEMBL2866586 | 0.92 | P2RX7 (0.53) | ALDH1A1ALOX15ITGB3ITGA2BP2RX7 | |
| SCHEMBL15020052 | 0.91 | ITGB3 (0.61) | ALDH1A1ITGB3ITGA2BP2RX7MEN1 | |
| SCHEMBL7318182 | 0.91 | ITGB3 (0.61) | ALDH1A1ITGB3ITGA2BP2RX7MEN1 | |
| SCHEMBL2855211 | 0.91 | ITGB3 (0.51) | ALDH1A1ALOX15ITGB3ITGA2BP2RX7 | |
| SCHEMBL2861161 | 0.91 | P2RX7 (0.59) | ALDH1A1ITGB3ITGA2BP2RX7MEN1 | |
| SCHEMBL2861160 | 0.91 | P2RX7 (0.59) | ALDH1A1ITGB3ITGA2BP2RX7MEN1 | |
| SCHEMBL2855213 | 0.91 | ITGB3 (0.51) | ALDH1A1ALOX15ITGB3ITGA2BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | claimed |
| US-9399653-B2 | Methods and systems for preparing irreversible inhibitors of protein tyrosine phosphatases | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-07-26 | — | — | US | disclosed |
| US-9399653-B2 | Methods and systems for preparing irreversible inhibitors of protein tyrosine phosphatases | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-07-26 | — | — | US | disclosed |
| US-20130165333-A1 | Methods and Systems for Preparing Irreversible Inhibitors of Protein Tyrosine Phosphatases | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-06-27 | — | — | US | disclosed |
| US-20130165333-A1 | Methods and Systems for Preparing Irreversible Inhibitors of Protein Tyrosine Phosphatases | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-06-27 | — | — | US | disclosed |
| EP-1346971-B1 | Production method for biarylalanine | SUMITOMO CHEMICAL CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-7091373-B2 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | ALDH1A1 1622/4885ALOX15 3612/4885ITGB3 4101/4885 |
| US-20130165333-A1 | Methods and Systems for Preparing Irreversible Inhibitors of Protein Tyrosine Phosphatases | SRMS, PTMS, PPM1A | ALDH1A1 3679/4885ALOX15 4769/4885ITGB3 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.