Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932676 | 0.72 | HPGD (0.40) | MAPTCISD1HPGDTDP1PTPN1 | |
| SCHEMBL8932678 | 0.72 | HPGD (0.40) | MAPTCISD1HPGDTDP1PTPN1 | |
| SCHEMBL8932685 | 0.71 | HDAC8 (0.53) | MAPTALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL8932730 | 0.69 | FFAR1 (0.42) | MAPTALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL8158239 | 0.66 | FFAR1 (0.58) | MAOAPPARGMAOBFFAR1PTPN1 | |
| SCHEMBL4857396 | 0.63 | PPARG (0.56) | MAPTALDH1A1PPARGMEN1TP53 | |
| SCHEMBL9570559 | 0.63 | MAPT (0.83) | MAPTALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL9573682 | 0.63 | PPARG (0.42) | MAPTALDH1A1NPSR1MAOACISD1 | |
| SCHEMBL1016492 | 0.61 | PPARG (0.57) | PPARGCYP3A4FFAR1PPARAHRH3 | |
| SCHEMBL13846702 | 0.61 | PPARG (0.59) | MAPTALDH1A1NPSR1MAOACISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |