Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592356 | 0.76 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2GAAMAOACYP1A2 | |
| SCHEMBL9663458 | 0.71 | PPARG (0.39) | KMT2ALMNASMN1; SMN2GAAHTT | |
| SCHEMBL9664286 | 0.69 | RAB9A (0.52) | CNR2KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL9663713 | 0.68 | RAB9A (0.45) | KMT2ALMNASMN1; SMN2GAAHTT | |
| SCHEMBL9663634 | 0.67 | RAB9A (0.62) | KMT2ALMNASMN1; SMN2GAAHTT | |
| SCHEMBL3284398 | 0.65 | AKR1C3 (0.57) | LMNATSHRPTGS2PTGS1AKR1C3 | |
| Diphenylmethanol SCHEMBL27594793 | 0.65 | SMN1; SMN2 (0.48) | KMT2ALMNASMN1; SMN2CA12CA1 | |
| Diphenylmethanol SCHEMBL11867320 | 0.64 | SMN1; SMN2 (0.52) | CNR2KMT2ALMNASMN1; SMN2CA12 | |
| SCHEMBL8869444 | 0.64 | LMNA (0.39) | KMT2ALMNASMN1; SMN2HTTNR3C1 | |
| SCHEMBL477559 | 0.63 | UGT2B7 (0.61) | KMT2ATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |