Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932685 | 0.81 | HDAC8 (0.53) | FFAR1PPARGMAOACISD1MAPT | |
| SCHEMBL8932729 | 0.69 | MAPT (0.38) | FFAR1PPARGMAOACISD1MAPT | |
| SCHEMBL10102375 | 0.69 | KDM4E (0.43) | MAPTEGFRPIK3CAALDH1A1NPSR1 | |
| SCHEMBL10515034 | 0.68 | FFAR1 (0.48) | FFAR1PPARGMAOACISD1MAPT | |
| SCHEMBL10102393 | 0.68 | BRD4 (0.55) | MAPTEGFRPIK3CAALDH1A1 | |
| SCHEMBL8932677 | 0.67 | PIM1 (0.47) | MAOACISD1MAOB | |
| SCHEMBL7164547 | 0.66 | FFAR1 (0.50) | FFAR1PPARGMAOACISD1MAPT | |
| SCHEMBL96600 | 0.66 | PPARG (0.48) | PPARGMAOACISD1MAPTALDH1A1 | |
| SCHEMBL8158239 | 0.66 | FFAR1 (0.58) | FFAR1PPARGMAOAMAOB | |
| SCHEMBL9830603 | 0.66 | FFAR1 (0.46) | FFAR1PPARGMAOACISD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026207-A1 | THIAZOLIDINE AND OXAZOLIDINE INDOLES WITH HYPOCLYCEMIC ACTIVITY | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-29 | — | — | WO | disclosed |