Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489531 | 0.91 | NPFFR1 (0.35) | MEN1ALDH1A1TSHRKMT2AOPRM1 | |
| SCHEMBL6477215 | 0.88 | JAK2 (0.37) | NAMPTOPRM1OPRK1SIGMAR1NPFFR1 | |
| Acetic Acid SCHEMBL6477357 | 0.87 | F2 (0.33) | MEN1ALDH1A1TSHRKMT2ANPC1L1 | |
| SCHEMBL7705663 | 0.86 | OPRM1 (0.32) | MEN1ALDH1A1TSHRKMT2AOPRM1 | |
| SCHEMBL5900915 | 0.82 | MEN1 (0.44) | MEN1ALDH1A1TSHRKMT2ANPC1L1 | |
| SCHEMBL8781179 | 0.80 | DPP4 (0.37) | — | |
| SCHEMBL6485866 | 0.79 | ITGB3 (0.33) | OPRM1OPRK1 | |
| SCHEMBL6476534 | 0.78 | JAK2 (0.36) | OPRM1OPRK1 | |
| SCHEMBL5900918 | 0.77 | MEN1 (0.45) | MEN1ALDH1A1TSHRKMT2ASIGMAR1 | |
| SCHEMBL6482023 | 0.77 | FAP (0.30) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |