Benzylamine

Benzylamine

SCHEMBL893344

NCc1ccccc1.c1ccc2c(c1)CC2

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.70
TAAR1 Q96RJ0 2/20 0.52
TSHR P16473 2/20 0.45
MAOB P27338 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTR2A P28223 2/20 0.45
RET P07949 1/20 0.45
CYP2A6 P11509 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GRIN2B Q13224 2/20 0.44
PNMT P11086 1/20 0.43
ENPP2 Q13822 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42
KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylamine SCHEMBL7398997 0.91 LOXL2 (0.64) LOXL2TAAR1TSHRMAOBCYP1A2
SCHEMBL24465564 0.89 LOXL2 (0.54) LOXL2TAAR1TSHRHTR2ARET
Benzylamine SCHEMBL373 0.84
Benzylamine SCHEMBL10707644 0.84 LOXL2 (1.00) LOXL2TAAR1TSHRMAOBCYP1A2
SCHEMBL19242392 0.84 LOXL2 (1.00) LOXL2TAAR1TSHRMAOBCYP1A2
Benzylamine SCHEMBL1331207 0.84
Benzylamine SCHEMBL5481672 0.84 LOXL2 (1.00) LOXL2TAAR1TSHRMAOBCYP1A2
Benzylamine SCHEMBL4306051 0.81
Benzylamine SCHEMBL20357787 0.81
Benzylamine SCHEMBL465924 0.81 LOXL2 (0.93) LOXL2TAAR1TSHRMAOBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190225889-A1 METHOD TO EXTRACT BITUMEN FROM OIL SANDS USING AROMATIC AMINES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-25 US claimed
WO-2018111342-A1 AMINE COMPOSITION FOR STEAM EXTRACTION OF BITUMEN DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-21 WO claimed
WO-2018017221-A1 METHOD TO EXTRACT BITUMEN FROM OIL SANDS USING AROMATIC AMINES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-25 WO claimed
US-9090736-B2 Rheological agent for radiation-curable coating compositions BASF SE (DE) 2015-07-28 US claimed
EP-2678364-B1 RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING MATERIALS BASF SE (DE) 2015-04-08 EP claimed
US-20120214894-A1 RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING COMPOSITIONS BASF SE (DE) 2012-08-23 US claimed
US-4357342-A 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid MERCK & CO., INC. (US) 1982-11-02 US claimed
EP-4682141-A1 TRICYCLIC COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2026-01-21 EP disclosed
US-20250188023-A1 BENZENE DERIVATIVE ONO PHARMACEUTICAL CO., LTD. (JP) 2025-06-12 US disclosed
US-12258308-B2 Benzene derivative ONO PHARMACEUTICAL CO., LTD. (JP) 2025-03-25 US disclosed
US-20240327342-A1 COMPOUNDS HAVING S1P5 RECEPTOR AGONISTIC ACTIVITY ONO PHARMACEUTICAL CO., LTD. (JP) 2024-10-03 US disclosed
EP-4431157-A2 1-[[(3S)-3-METHYL-6-(4(4,4-TRIFLUOROBUTOXY)-3,4-DIHYDRONAPHTHALEN-2YL]METHYL]AZETIDINE-3-CARBOXYLIC ACID HAVING S1P5 RECEPTOR AGONIST ACTIVITY FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS AND CANCER ONO Pharmaceutical Co., Ltd. (JP) 2024-09-18 EP disclosed
US-12049445-B2 Compounds having S1P5 receptor agonistic activity ONO PHARMACEUTICAL CO., LTD. (JP) 2024-07-30 US disclosed
EP-0134301-A1 6-(1'-Hydroxyethyl)-3-substituted amino-1-azabicyclo(3.2.0)-hept-2-en-7-one-2-carboxylic acid MERCK & CO. INC. (US) 1985-03-20 EP disclosed
US-4424230-A CARBAPENICILLIN ANTIBIOTICS MERCK & CO., INC. (US) 1984-01-03 US disclosed
EP-0071395-A1 Beta-lactam antibacterial agents BEECHAM GROUP PLC (GB) 1983-02-09 EP disclosed
US-4369187-A AMINO ACID DERIVATIVE ANTIBIOTICS MERCK & CO., INC. (US) 1983-01-18 US disclosed
US-4357342-A 1-Azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylic acid MERCK & CO., INC. (US) 1982-11-02 US disclosed
EP-0055062-A1 Compounds containing beta-lactams BEECHAM GROUP PLC (GB) 1982-06-30 EP disclosed
US-4310538-A BACTERICIDES MERCK & CO., INC. (US) 1982-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12049445-B2 Compounds having S1P5 receptor agonistic activity S1PR5, S1PR1, S1PR4 LOXL2 2283/4885TAAR1 235/4885TSHR 625/4885
US-12258308-B2 Benzene derivative PMP22, TMBIM6, MYT1 LOXL2 3622/4885TAAR1 3233/4885TSHR 4497/4885
US-20240327342-A1 COMPOUNDS HAVING S1P5 RECEPTOR AGONISTIC ACTIVITY S1PR5, S1PR1, S1PR4 LOXL2 2283/4885TAAR1 235/4885TSHR 625/4885
US-20250188023-A1 BENZENE DERIVATIVE PMP22, TMBIM6, MYT1 LOXL2 3710/4885TAAR1 3232/4885TSHR 4501/4885
US-20120214894-A1 RHEOLOGICAL AGENT FOR RADIATION-CURABLE COATING COMPOSITIONS RAD51, XRCC6, XRCC5 LOXL2 3457/4885TAAR1 3042/4885TSHR 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.