Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11721186 | 0.83 | KDM4E (0.50) | KDM4EAPEX1PDE4APDE4BPDE4C | |
| SCHEMBL25465029 | 0.82 | PTGS1 (0.57) | PTGS1PTGS2APEX1MEN1KMT2A | |
| SCHEMBL25465028 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2APEX1MEN1KMT2A | |
| SCHEMBL517606 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL15007818 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL699936 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL25293705 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL25293609 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL42735 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 | |
| SCHEMBL25288050 | 0.74 | KMT2A (0.52) | KDM4EMEN1FAAHTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | claimed |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | claimed |
| US-6392041-B1 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | claimed |
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2002-05-16 | — | — | US | claimed |
| US-20120083557-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2012-04-05 | — | — | US | disclosed |
| US-6872832-B2 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | disclosed |
| US-6392041-B1 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | disclosed |
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2002-05-16 | — | — | US | disclosed |
| US-6376584-B1 | OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083557-A1 | STERICALLY HINDERED AMINE STABILIZERS | AAAS, H1-5, H1-2 | PTGS1 3600/4885PTGS2 3312/4885KDM4E 456/4885 |
| US-20020058735-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, HAO2, POLH | PTGS1 4084/4885PTGS2 3739/4885KDM4E 678/4885 |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, POLH, OGFOD1 | PTGS1 4291/4885PTGS2 4026/4885KDM4E 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.