SCHEMBL8933923

SCHEMBL8933923

O=[N+]([O-])n1nnc2c(O)cccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.36
KDM4E B2RXH2 4/20 0.36
NPC1 O15118 3/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
CHRM1 P11229 2/20 0.36
METAP2 P50579 2/20 0.36
BRD4 O60885 1/20 0.36
LMNA P02545 1/20 0.36
CTSB P07858 1/20 0.36
HSP90AA1 P07900 1/20 0.36
DRD2 P14416 1/20 0.36
ALOX12 P18054 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2C P28335 1/20 0.36
CTH P32929 1/20 0.36
PTGS2 P35354 1/20 0.36
HRH1 P35367 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3767410 0.73 ACHE (0.39) RAB9AKDM4EALDH1A1MAPTCHRM1
SCHEMBL277629 0.72 KMT2A (0.49) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL378660 0.71 POLB (0.50) RAB9AKDM4EALDH1A1MAPTCHRM1
Silver SCHEMBL11416599 0.70 KMT2A (0.48) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL11503462 0.70 KMT2A (0.48) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL8907627 0.70 KCNMA1 (0.45) RAB9AKDM4EMAPTCHRM1METAP2
SCHEMBL28421250 0.70 TSHR (0.33) KDM4EALDH1A1MAPTSMN1; SMN2TDP1
Water SCHEMBL3673310 0.69 POLB (0.48) RAB9AKDM4EALDH1A1MAPTCHRM1
SCHEMBL8425686 0.69 ACHE (0.39) RAB9AKDM4EALDH1A1MAPTCHRM1
SCHEMBL8146888 0.69 MAPT (0.48) RAB9AKDM4EALDH1A1MAPTCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554744-A Method for loading solid supports for nucleic acid synthesis HYBRIDON, INC. (US) 1996-09-10 US claimed
WO-1996009314-A2 METHOD FOR LOADING SOLID SUPPORTS FOR NUCLEIC ACID SYNTHESIS HYBRIDON, INC. (US) 1996-03-28 WO claimed