1-Methylimidazole

1-Methylimidazole

SCHEMBL893393

CCOCC.Cn1ccnc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 2/20 0.68
NFKB1 P19838 1/20 0.68
HSD17B10 Q99714 1/20 0.68
QPCTL Q9NXS2 1/20 0.68
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
TBXAS1 P24557 3/20 0.39
LMNA P02545 1/20 0.38
NPSR1 Q6W5P4 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.32
PRKCI P41743 1/20 0.32
EGLN3 Q9H6Z9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Methylimidazole SCHEMBL28322686 0.98 QPCT (0.65) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL29133572 0.92 NFKB1 (0.58) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL28572517 0.92 NFKB1 (0.58) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL29133570 0.90 NFKB1 (0.56) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL29242961 0.89 NFKB1 (0.54) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL28357920 0.86 NFKB1 (0.68) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL27704930 0.85
1-Methylimidazole SCHEMBL28729449 0.83 QPCT (0.79) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL28253626 0.83 QPCT (0.79) QPCTNFKB1HSD17B10QPCTLALDH1A1
1-Methylimidazole SCHEMBL28183086 0.83 QPCT (0.79) QPCTNFKB1HSD17B10QPCTLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107915642-B Separation method of dimethyl carbonate and methanol 中国石油化工股份有限公司 2024-06-28 CN claimed
CN-116626788-B Electrowetting zoom lens based on high-refractive-index ionic liquid 季华实验室 2023-11-24 CN claimed
CN-116626788-A Electrowetting zoom lens based on high-refractive-index ionic liquid 季华实验室 2023-08-22 CN claimed
CN-113270644-A Electrolyte and preparation method and application thereof 惠州亿纬锂能股份有限公司 2021-08-17 CN claimed
CN-116626788-B Electrowetting zoom lens based on high-refractive-index ionic liquid 季华实验室 2023-11-24 CN disclosed
CN-116626788-A Electrowetting zoom lens based on high-refractive-index ionic liquid 季华实验室 2023-08-22 CN disclosed
CN-113270644-A Electrolyte and preparation method and application thereof 惠州亿纬锂能股份有限公司 2021-08-17 CN disclosed
CN-110372678-A A kind of synthetic method of high-purity crown ether functionalized ion liquid 山西大学 2019-10-25 CN disclosed
CN-106215852-B A kind of method of fluorine-containing organic gas purifying 浙江博瑞电子科技有限公司 2019-10-22 CN disclosed
CN-104803912-B A kind of synthetic method of medicine intermediate quinoline compound 青岛大学 2017-03-08 CN disclosed
US-9573915-B2 Ionic liquids, the method for preparing the same and method for removing acetylenes from olefin mixtures using the ionic liquids KOLON INDUSTRIES, INC. (KR) 2017-02-21 US disclosed
US-20140296523-A1 Ionic Liquids, The Method For Preparing The Same And Method For Removing Acetylenes From Olefin Mixtures Using The Ionic Liquids KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-10-02 US disclosed
US-8785711-B2 Ionic liquids, the method for preparing the same and method for removing acetylenes from olefin mixtures using the ionic liquids KOLON INDUSTRIES, INC. (KR) 2014-07-22 US disclosed
US-20120083642-A1 IONIC LIQUIDS, THE METHOD FOR PREPARING THE SAME AND METHOD FOR REMOVING ACETYLENES FROM OLEFIN MIXTURES USING THE IONIC LIQUIDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120083642-A1 IONIC LIQUIDS, THE METHOD FOR PREPARING THE SAME AND METHOD FOR REMOVING ACETYLENES FROM OLEFIN MIXTURES USING THE IONIC LIQUIDS AOX1, ACOX1, AOC2 QPCT 4032/4885NFKB1 3997/4885HSD17B10 582/4885
US-20140296523-A1 Ionic Liquids, The Method For Preparing The Same And Method For Removing Acetylenes From Olefin Mixtures Using The Ionic Liquids AOX1, ACOX1, AOC2 QPCT 4032/4885NFKB1 3997/4885HSD17B10 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.