SCHEMBL8934025

SCHEMBL8934025

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)cc2F)CC1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2B Q13224 1/20 0.36
DGAT1 O75907 1/20 0.36
MGLL Q99685 4/20 0.35
OPRL1 P41146 8/20 0.34
TDP2 O95551 1/20 0.34
FPR2 P25090 1/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8934309 0.99 MGLL (0.36) NAAAGRIN1GRIN2BDGAT1MGLL
SCHEMBL8960707 0.97 NAAA (0.34) NAAAGRIN1GRIN2BDGAT1MGLL
SCHEMBL8960823 0.96 MGLL (0.35) NAAAGRIN1GRIN2BDGAT1MGLL
SCHEMBL8934063 0.93 NAAA (0.37) NAAAGRIN1GRIN2BDGAT1OPRL1
SCHEMBL8934124 0.92 OPRL1 (0.34) NAAAGRIN1GRIN2BDGAT1OPRL1
SCHEMBL8934128 0.91 S1PR1 (0.35) GRIN1GRIN2BDGAT1OPRL1FPR2
SCHEMBL8934342 0.91 OPRL1 (0.34) NAAAGRIN1GRIN2BDGAT1OPRL1
SCHEMBL8934119 0.91 OPRL1 (0.34) DGAT1OPRL1FPR2
SCHEMBL8934938 0.91 FPR2 (0.36) FPR2ALOX5APFEN1
SCHEMBL8934130 0.90 PTPN11 (0.35) DGAT1OPRL1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed