Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 9/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934321 | 0.93 | LTA4H (0.40) | LTA4HRETPYGLHTR2CSLC6A3 | |
| SCHEMBL9080768 | 0.87 | LTA4H (0.46) | LTA4HRETKMT2AHTR2CSLC6A3 | |
| SCHEMBL8934363 | 0.86 | MTNR1A (0.41) | LTA4HRETKMT2AMTNR1AMTNR1B | |
| SCHEMBL8934364 | 0.80 | MTNR1A (0.39) | LTA4HRETKMT2AMTNR1AMTNR1B | |
| SCHEMBL9081168 | 0.80 | HTR2C (0.47) | LTA4HRETHTR2CSLC6A3 | |
| SCHEMBL8934341 | 0.79 | LTA4H (0.40) | LTA4HRETKMT2A | |
| SCHEMBL9080775 | 0.75 | HTR2C (0.47) | LTA4HRETHTR2CSLC6A3 | |
| SCHEMBL8934441 | 0.73 | NR1I2 (0.43) | LTA4HRETKMT2A | |
| SCHEMBL8934348 | 0.73 | SLC6A4 (0.39) | LTA4HRETKMT2AHTR2CSLC6A3 | |
| SCHEMBL9093322 | 0.72 | LTA4H (0.47) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031480-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |