Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080768 | 0.88 | LTA4H (0.46) | HTR2CSLC6A3L3MBTL1GAAOPRM1 | |
| SCHEMBL9081168 | 0.83 | HTR2C (0.47) | HTR2CSLC6A3RETLTA4H | |
| SCHEMBL9081150 | 0.81 | HTR2C (0.50) | HTR2CSLC6A3L3MBTL1GAAOPRM1 | |
| SCHEMBL8934367 | 0.75 | LTA4H (0.42) | HTR2CSLC6A3RETLTA4H | |
| SCHEMBL9081312 | 0.75 | PPARG (0.40) | HTR2CSLC6A3RETHTTCHRM1 | |
| SCHEMBL30729415 | 0.75 | RET (0.66) | HTR2CSLC6A3OPRM1RETCHRM2 | |
| SCHEMBL8934363 | 0.73 | MTNR1A (0.41) | HTR2CRETLTA4H | |
| SCHEMBL8715328 | 0.73 | RET (0.44) | RET | |
| SCHEMBL8712643 | 0.73 | RET (0.44) | RET | |
| SCHEMBL8934341 | 0.73 | LTA4H (0.40) | L3MBTL1RETLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031460-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031460-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |