Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | MAOB | P27338 | 4/20 | 0.75 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | GAPDH | P04406 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.67 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177366 | 0.86 | RAB9A (1.00) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL30356319 | 0.86 | RAB9A (1.00) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL3490539 | 0.83 | MAOB (0.71) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL250083 | 0.83 | RAB9A (0.79) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL29517170 | 0.82 | RAB9A (0.78) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL24055368 | 0.81 | RAB9A (0.66) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL24055369 | 0.81 | KDM4E (0.66) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL2929526 | 0.80 | ALDH1A1 (0.75) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL23212283 | 0.80 | RAB9A (0.75) | KDM4ERAB9AALDH1A1MAOBNPC1 | |
| SCHEMBL4064740 | 0.80 | ALDH1A1 (1.00) | KDM4ERAB9AALDH1A1MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |