Famprofazone

Famprofazone

SCHEMBL893453

CC(C)c1c(CN(C)C(C)Cc2ccccc2)n(C)n(-c2ccccc2)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
NR1I2 O75469 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
TSHR P16473 1/20 1.00
CYP2C19 P33261 1/20 1.00
PTGS2 P35354 4/20 0.53
ADORA3 P0DMS8 1/20 0.52
ADRA2B P18089 2/20 0.50
ADRA2C P18825 2/20 0.50
ADRA1A P35348 2/20 0.50
OPRK1 P41145 2/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2A P28223 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
KCNH2 Q12809 1/20 0.50
POLB P06746 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Famprofazone SCHEMBL893454 1.00 LMNA (1.00) LMNANR1I2CYP3A4CYP2D6CYP2C9
SCHEMBL4327273 0.86 LMNA (0.75) LMNANR1I2CYP3A4CYP2D6CYP2C9
SCHEMBL11287540 0.75 LMNA (0.65) LMNANR1I2CYP3A4CYP2D6CYP2C9
SCHEMBL3526669 0.75 LMNA (0.65) LMNANR1I2CYP3A4CYP2D6CYP2C9
SCHEMBL3527994 0.72 LMNA (0.60) LMNANR1I2CYP3A4CYP2D6CYP2C9
Propyphenazone SCHEMBL27899010 0.71 LMNA (0.70) LMNANR1I2CYP3A4CYP2D6CYP2C9
Propyphenazone SCHEMBL23393 0.70 LMNA (1.00) LMNACYP2D6PTGS2ADORA3POLB
Benzphetamine SCHEMBL678807 0.69 ADRA2B (1.00) LMNANR1I2CYP3A4CYP2D6CYP2C9
Benzphetamine SCHEMBL49120 0.69 ADRA2B (1.00) LMNANR1I2CYP3A4CYP2D6CYP2C9
Benzphetamine SCHEMBL19285634 0.69 ADRA2B (1.00) LMNANR1I2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ACERAGEN INC (US) 2026-01-01 US claimed
US-20230321073-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION Response IP Holding Company, LLC (US) 2023-10-12 US claimed
EP-4192579-A2 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION Response IP Holding Company, LLC (US) 2023-06-14 EP claimed
US-20220387466-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF DYSBIOSIS AND ANTIBACTERIAL ANTIDOTES FOR MICROBIOME-PROTECTION EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2022-12-08 US claimed
EP-4076411-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF DYSBIOSIS AND ANTIBACTERIAL ANTIDOTES FOR MICROBIOME-PROTECTION European Molecular Biology Laboratory (DE) 2022-10-26 EP claimed
US-20220088158-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ROIVANT SCIENCES, INC. 2022-03-24 US claimed
WO-2022032077-A2 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION REDUX THERAPEUTICS, LLC (US) 2022-02-10 WO claimed
WO-2021122809-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF DYSBIOSIS AND ANTIBACTERIAL ANTIDOTES FOR MICROBIOME-PROTECTION EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2021-06-24 WO claimed
EP-3838269-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND/OR TREATMENT OF DYSBIOSIS AND ANTIBACTERIAL ANTIDOTES FOR MICROBIOME-PROTECTION European Molecular Biology Laboratory (DE) 2021-06-23 EP claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-2188630-A2 METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS THE UNIVERSITY OF ROCHESTER (US) 2010-05-26 EP claimed
WO-2009045443-A2 METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS THE UNIVERSITY OF ROCHESTER (US) 2009-04-09 WO claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-6929805-B2 For oral administration comprising an analgesic with rapid onset of action and at least one systemically acting analgesic with sustained action, such as a combination of benzocaine and acetylsalicylic acid (ASA) BAYER AKTIENGESELLSCHAFT (DE) 2005-08-16 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-4181719-A Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates STERLING DRUG INC. (US) 1980-01-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321073-A1 COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION LIPC, CPT1A, CETP LMNA 2305/4885NR1I2 1320/4885CYP3A4 1150/4885
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ASAH2, ASAH1, GBA2 LMNA 1898/4885NR1I2 1617/4885CYP3A4 4420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.