Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934613 | 0.82 | ATP4A (0.54) | MAPTHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL16386296 | 0.81 | ATP4A (0.55) | MAPTHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL9045517 | 0.80 | MAPT (0.54) | MAPTLMNATSHRSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL826626 | 0.75 | MAPT (0.47) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL827382 | 0.74 | ATP4A (0.63) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9047133 | 0.73 | RAB9A (0.60) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9048064 | 0.72 | MAPT (0.47) | MAPTLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL22296554 | 0.70 | HRH2 (0.53) | MAPTHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL22296507 | 0.70 | ATP4A (0.41) | MAPTHRH2SLC22A2CA12SLC22A3 | |
| SCHEMBL823916 | 0.69 | LMNA (0.52) | MAPTCA12CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |